Research Progress of Nanotechnology Treating for Brain Glioma

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January 01, 2018.   doi:10.12123/npcd201801005

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Ran Chen, Yi Li, Rennan Weng*

Department of Zhongshan School of Medicine, Sun Yat-Sen University, Guangzhou, 510275, P. R . China

Communication: wengrn@mail2.sysu.edu.cn

Keywords: Nanotechnology; Brain glioma; Treatment

Received: September 01,2017 Accept: November 01,2017 published:January 01,2018

ABSTRACT

With its highly proliferative, infiltrative, and invasive properties, glioma is the most common malignant primary brain tumor, and 57% of them are glioblastoma multiforme, with a median survival time of only 18 months. However, facing the great challenges from blood-brain barrier and blood-brain tumor barrier, the drug treating for glioma remain non-targeted with low efficiency, which urgently need a new drug. Due to its plastic, low-toxic, targeted nature, nanotechnology brings hope to glioma treatment. In this review, we will discuss the potential possibility of nanoparticles in the treatment of gliomas based on targeted drug delivery system.

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